A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis

Autor: Dierig, A1,2 (AUTHOR), Hoelscher, M1,2 (AUTHOR), Schultz, S1,2 (AUTHOR), Hoffmann, L1,2 (AUTHOR), Jarchow-MacDonald, A1,2,3 (AUTHOR), Svensson, EM4,5 (AUTHOR), Te Brake, L4 (AUTHOR), Aarnoutse, R4 (AUTHOR), Boeree, M4 (AUTHOR), McHugh, TD6 (AUTHOR), Wildner, LM6 (AUTHOR), Gong, X7 (AUTHOR), Phillips, PPJ7 (AUTHOR), Minja, LT8 (AUTHOR), Ntinginya, N8 (AUTHOR), Mpagama, S9 (AUTHOR), Liyoyo, A9 (AUTHOR), Wallis, RS10 (AUTHOR), Sebe, M10 (AUTHOR), Mhimbira, FA11 (AUTHOR)
Zdroj: Trials. 6/6/2023, Vol. 24 Issue 1, p1-15. 15p. 1 Diagram, 2 Charts.
Databáze: Academic Search Ultimate
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