Elraglusib (9-ING-41), a selective small-molecule inhibitor of glycogen synthase kinase-3 beta, reduces expression of immune checkpoint molecules PD-1, TIGIT and LAG-3 and enhances CD8+ T cell cytolytic killing of melanoma cells.

Autor: Shaw, Gary1 (AUTHOR), Cavalcante, Ludimila2 (AUTHOR), Giles, Francis J.3 (AUTHOR), Taylor, Alison1 (AUTHOR) a.taylor1@leeds.ac.uk
Zdroj: Journal of Hematology & Oncology. 9/14/2022, Vol. 15 Issue 1, p1-13. 13p.
Databáze: Academic Search Ultimate
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