Prediction of human pharmacokinetics for low‐clearance compounds using pharmacokinetic data from chimeric mice with humanized livers.

Autor: Yoshida, Kosuke1,2 (AUTHOR) yoshida.kousuke@mf.mt-pharma.co.jp, Doi, Yuki1 (AUTHOR), Iwazaki, Norihiko1 (AUTHOR), Yasuhara, Hidenori1 (AUTHOR), Ikenaga, Yuka1 (AUTHOR), Shimizu, Hidetoshi1 (AUTHOR), Nakada, Tomohisa1 (AUTHOR), Watanabe, Tomoko1 (AUTHOR), Tateno, Chise3 (AUTHOR), Sanoh, Seigo2 (AUTHOR), Kotake, Yaichiro2 (AUTHOR)
Zdroj: CTS: Clinical & Translational Science. Jan2022, Vol. 15 Issue 1, p79-91. 13p.
Databáze: Academic Search Ultimate
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