Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice.

Autor: Birkisdóttir, María B.1 (AUTHOR), Jaarsma, Dick2 (AUTHOR), Brandt, Renata M. C.3 (AUTHOR), Barnhoorn, Sander3 (AUTHOR), Vliet, Nicole3 (AUTHOR), Imholz, Sandra4 (AUTHOR), Oostrom, Conny T.4 (AUTHOR), Nagarajah, Bhawani4 (AUTHOR), Portilla Fernández, Eliana5 (AUTHOR), Roks, Anton J. M.5 (AUTHOR), Elgersma, Ype2 (AUTHOR), Steeg, Harry4 (AUTHOR), Ferreira, José A.6 (AUTHOR), Pennings, Jeroen L. A.4 (AUTHOR), Hoeijmakers, Jan H. J.1,3,7 (AUTHOR), Vermeij, Wilbert P.1 (AUTHOR) W.P.Vermeij@prinsesmaximacentrum.nl, Dollé, Martijn E. T.4 (AUTHOR) Martijn.Dolle@rivm.nl
Zdroj: Aging Cell. Feb2021, Vol. 20 Issue 2, p1-17. 17p.
Databáze: Academic Search Ultimate