Chemoselective Hydrogenation of 6‐Alkynyl‐3‐fluoro‐2‐pyridinaldoximes: Access to First‐in‐Class 6‐Alkyl‐3‐Fluoro‐2‐pyridinaldoxime Scaffolds as New Reactivators of Sarin‐Inhibited Human Acetylcholinesterase with Increased Blood–Brain Barrier Permeability

Autor: Yerri, Jagadeesh1 (AUTHOR), Dias, José2 (AUTHOR), Nimmakayala, Mallikajurna Reddy1 (AUTHOR), Razafindrainibe, Franck1 (AUTHOR), Courageux, Charlotte2 (AUTHOR), Gastellier, Anne‐Julie2 (AUTHOR), Jegoux, Johanne2 (AUTHOR), Coisne, Caroline3 (AUTHOR), Landry, Christophe3 (AUTHOR), Gosselet, Fabien3 (AUTHOR), Hachani, Johan3 (AUTHOR), Goossens, Jean‐François4 (AUTHOR), Dehouck, Marie‐Pierre3 (AUTHOR), Nachon, Florian2 (AUTHOR), Baati, Rachid1 (AUTHOR) rachid.baati@unistra.fr
Zdroj: Chemistry - A European Journal. 11/20/2020, Vol. 26 Issue 65, p15035-15044. 10p.
Databáze: Academic Search Ultimate
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