The antiarrhythmic compound efsevin directly modulates voltage-dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca2+ uptake.

Autor: Wilting, Fabiola1 (AUTHOR), Kopp, Robin1 (AUTHOR), Gurnev, Philip A.2 (AUTHOR), Schedel, Anna1 (AUTHOR), Dupper, Nathan J.3 (AUTHOR), Kwon, Ohyun3 (AUTHOR), Nicke, Annette1 (AUTHOR), Gudermann, Thomas1,4 (AUTHOR), Schredelseker, Johann1 (AUTHOR) johann.schredelseker@lmu.de
Zdroj: British Journal of Pharmacology. Jul2020, Vol. 177 Issue 13, p2947-2958. 12p. 5 Graphs.
Databáze: Academic Search Ultimate