The iron chelator Deferasirox causes severe mitochondrial swelling without depolarization due to a specific effect on inner membrane permeability.

Autor: Gottwald, Esther M.1, Schuh, Claus D.1, Drücker, Patrick2, Haenni, Dominik1,3, Pearson, Adam1, Ghazi, Susan1, Bugarski, Milica1, Polesel, Marcello1, Duss, Michael4, Landau, Ehud M.4, Kaech, Andres3, Ziegler, Urs3, Lundby, Anne K. M.5, Lundby, Carsten5, Dittrich, Petra S.2, Hall, Andrew M.1,6 andrew.hall@uzh.ch
Zdroj: Scientific Reports. 1/31/2020, Vol. 10 Issue 1, p1-15. 15p.
Databáze: Academic Search Ultimate
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