Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates.

Autor: Ellsworth, Jeff L.1 (AUTHOR) jellsworth@homologymedicines.com, Gingras, Jacinthe1 (AUTHOR), Smith, Laura J.1 (AUTHOR), Rubin, Hillard1 (AUTHOR), Seabrook, Tania A.1 (AUTHOR), Patel, Kruti1 (AUTHOR), Zapata, Nicole1 (AUTHOR), Olivieri, Kevin1 (AUTHOR), O'Callaghan, Michael1 (AUTHOR), Chlipala, Elizabeth2 (AUTHOR), Morales, Pablo3 (AUTHOR), Seymour, Albert1 (AUTHOR)
Zdroj: PLoS ONE. 11/26/2019, Vol. 14 Issue 11, p1-33. 33p.
Databáze: Academic Search Ultimate
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