Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.

Autor: Chun-Xiang Wu1,2, Jingling Liao1,2,3, Yangshin Park1,2, Xylena Reed4, Engel, Victoria A.1,2, Hoang, Neo C.1,2, Yuichiro Takagi1, Johnson, Steven M.1, Mu Wang1,5, Federici, Mark6, Nichols, R. Jeremy7, Sanishvili, Ruslan8, Cookson, Mark R.4, Hoang, Quyen Q.1,2,9 qqhoang@iu.edu
Zdroj: Journal of Biological Chemistry. 4/12/2019, Vol. 294 Issue 15, p5907-5913. 7p.
Databáze: Academic Search Ultimate