Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.

Autor: Lorendeau, Doriane1,2, Rinaldi, Gianmarco1,2, Boon, Ruben3,4, Spincemaille, Pieter5, Metzger, Kristine1,2, Jäger, Christian6, Christen, Stefan1,2, Dong, Xiangyi6, Kuenen, Sabine7,8, Voordeckers, Karin9,10, Verstreken, Patrik7,8, Cassiman, David11, Vermeersch, Pieter5,12, Verfaillie, Catherine3,4, Hiller, Karsten6, Fendt, Sarah-Maria1,2 sarah-maria.fendt@vib-kuleuven.be
Zdroj: Metabolic Engineering. Sep2017 Part B, Vol. 43, p187-197. 11p.
Databáze: Academic Search Ultimate