The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome.
Autor: | Yi, Jason J.1, Paranjape, Smita R.2,3, Walker, Matthew P.2,4, Choudhury, Rajarshi4,5, Wolter, Justin M.2,3, Fragola, Giulia2,3, Emanuele, Michael J.4,5, Major, Michael B.2,4, Zylka, Mark J.1,2,6 zylka@med.unc.edu |
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Zdroj: | Journal of Biological Chemistry. 7/28/2017, Vol. 292 Issue 30, p12503-12515. 13p. |
Databáze: | Academic Search Ultimate |
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