Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme.

Autor: Hutschenreuter, Tilman U.1, Ehmer, Peter B.1, Hartmann, Rolf W.1 rwh@mx.uni-saarland.de
Zdroj: Journal of Enzyme Inhibition & Medicinal Chemistry. Feb2004, Vol. 19 Issue 1, p17-32. 16p. 8 Diagrams, 3 Charts, 2 Graphs.
Databáze: Academic Search Ultimate