Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.
| Autor: | Dorywalska, Magdalena1, Strop, Pavel1 pavel.strop@pfizer.com, Melton-Witt, Jody A.1, Hasa-Moreno, Adela1, Farias, Santiago E.1, Galindo Casas, Meritxell1, Delaria, Kathy1, Lui, Victor1, Poulsen, Kris1, Sutton, Janette1, Bolton, Gary1, Zhou, Dahui2, Moine, Ludivine2, Dushin, Russell2, Tran, Thomas-Toan1, Liu, Shu-Hui1, Rickert, Mathias1, Foletti, Davide1, Shelton, David L.1, Pons, Jaume1 |
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| Zdroj: | PLoS ONE. 7/10/2015, Vol. 10 Issue 7, p1-14. 14p. |
| Databáze: | Academic Search Ultimate |
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