| Autor: |
Hendy, Christopher H.1, Djamgoz, Mustafa B. A.1 |
| Předmět: |
|
| Zdroj: |
Pesticide Science. 1988, Vol. 24 Issue 4, p289-298. 10p. |
| Abstrakt: |
The effect of deltamethrin (10μm) on extracellular K+ activity in the micro-environment of the central nervous system of the cockroach has been studied. At normal room temperature, deltamethrin induced a rise in the K+ concentration of about 3 mM, representing some 75% increase from normal Deltamethrin also caused a transient surge in the frequency of spontaneous activity, which preceded the K+ effect. At a lowered temperature, the final value of the deltamthrin-induced rise in extracellular K+ concentration was very similar to normal. However, when the structural component of the blood-brain barrier was disrupted, the effect of deltamethrin was much reduced. Possible consequences of the deltamethrin-induced rise in extracellular K+ concentration and the potential role of the blood-brain barrier in insecticide action are discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
GreenFILE |
| Externí odkaz: |
|
Plný text