| Autor: |
Zerba, E., de Licastro, S. A., Masuh, H., Picollo, M. I., Audino, P. G., Vassena, C. |
| Předmět: |
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| Zdroj: |
Pesticide Science. Apr1997, Vol. 49 Issue 4, p339. 0p. |
| Abstrakt: |
A series of methyl esters of N-substituted (Z)- and (E)-maleamic acids were synthesized and their effect on food intake measured on fifth-instar nymphs of Triatoma infestans. Suppression of food intake was found only for the (Z)-isomers. The initial reaction rate of the synthesized compounds with glutathione (GSH) was calculated from the reaction in vitro of the (Z)-isomers. No reaction was observed with the (E)-isomers. Good correlation between the suppression of food intake, measured by its ED50 (effective dose that inhibited feeding of 50% of the population) and the initial reaction rate with GSH and the hydrophobic parameter pi, was found. [ABSTRACT FROM AUTHOR] |
| Databáze: |
GreenFILE |
| Externí odkaz: |
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