Evaluation of the annual killifish Nothobranchius guentheri as a tool for rapid acute toxicity screening

Autor: Hull, E., Shedd, T. R., Toussaint, M. W., Sunkel, M. C., Widder, M. W.
Předmět:
Zdroj: Environmental Toxicology & Chemistry. Oct1999, Vol. 18 Issue 10, p2258. 0p.
Abstrakt: This study evaluated the use of Nothobranchius guentheri as a novel organism for rapid acute toxicity screening. A major advantage of thespecies is that there is no need to maintain a continuous culture tohave organisms immediately available for testing. Rather, the embryos are viable under long-term storage conditions and can be hatched within a few hours. The tests require only 24 h with standard laboratory equipment. Sensitivity levels for 11 representative toxicants were comparable to those reported for five of the standard U.S. Environmental Protection Agency test species requiring continuous culture. [ABSTRACT FROM AUTHOR]
Databáze: GreenFILE