| Autor: |
Heinevetter, D.1, Lewerenz, H.J.1, Plass, R.1, Macholz, R.1 |
| Zdroj: |
Journal of Environmental Science & Health. Part B. Pesticides, Food Contaminants & Agricultural Wastes. Jan1985, Vol. 20 Issue 5, p539-558. 20p. |
| Abstrakt: |
In vitro investigations of the influence of lindane and its metabolites were performed on microsomal and mitochondrial ATPases from liver, kidney and brain of rat and mouse. The microsomal Na+‐K+‐ATPases in rat liver were inhibited by the tested substances. An increase of activity was observed only with 2,5 × 10 M‐5 gamma‐HCH. Effects on the microsomal Na+‐K+‐ATPase from kidney and brain of rat were also indicated. The mitochondrial enzym in rat liver was stimulated by all the compounds tested at concentrations of 10‐4 M – 10‐2 M. The effects on raitochondrial enzymes from kidney and brain varied in dependence on the tested substances. In the microsomes and mitochondria of mouse an influence on the Na+‐K+‐ATPases similar to the effects on the preparations from organs of rat was evident. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
GreenFILE |
| Externí odkaz: |
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