Autor: |
Shi Feng Yun1, Xiao Yun Tian1, Shu Pei Cheng2 chengsp@nju.edu.cn, Yan Zhang2, Ai Min Li2, Li Bo Zhang1, Xu Xiang Zhang2, Li Chen1, Bing Wu2, Lian Qin Guo1, Yun zhong Shi3 |
Předmět: |
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Zdroj: |
Ecotoxicology. Jul2011, Vol. 20 Issue 5, p1078-1082. 5p. |
Abstrakt: |
The 18 biochemical parameters of serum were measured to analyze the pathogenic risks of the Yangtze River Source of Drinking Water in Nanjing area (YZR-SDW-NJ) on mouse Mus musculus for protection of human health in this research. The male mice Mus musculus were sampled and fed with YZR-SDW-NJ for 90 days then the eighteen serum biochemical levels were measured with Automatic Biochemical Analysis/RerLi 600. And the parameter data were treated by One-Way ANOVA statistic approach. The results showed that five parameter levels for the sample group mice were different from those for the control group significantly (0.01 < P or 0.05 < P). Four 4 of the 5 altered parameter levels were decreased including glutamate pyruvate transaminase 38% lower, glutamine-oxaloacetic transaminase 24% lower, triglyceride 76% lower and cystatin C 73% lower, only creatinine level was 26% higher than that in the control group. The data suggest that YZR-SDW-NJ had toxicity on the mouse and the organic pollutants in YZR-SDW-NJ might lead to liver, kidney, cardiovascular and metabolic pathogenic risks on the human beings. The results might be cited as evidence to control pollutants in the source water for the protection of NJ people's health. [ABSTRACT FROM AUTHOR] |
Databáze: |
GreenFILE |
Externí odkaz: |
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