| Autor: |
Zavala-Aguirre, José Luis1 jzavala@uag.mx, Torres-Bugarín, Olivia2, Buelna-Osben, Héctor René3, Flores-Kehn, Lola Paulina1, Ramos-Ibarra, María Luisa4, Zúñiga-González, Guillermo5, Ogura, Tetsuya6 |
| Předmět: |
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| Zdroj: |
Journal of Environmental Science & Health. Part A. Toxic/Hazardous Substances & Environmental Engineering. Jan2010, Vol. 45 Issue 1, p75-81. 7p. 1 Chart, 2 Graphs. |
| Abstrakt: |
This study is a follow-up of previous research in which we described the frequency of spontaneous micronucleated erythrocytes (MNE) in the Goodeid Xenotocoa melanosoma collected from Lake La Alberca, located in the state of Michoacan, Mexico. In the present work, we measured micronuclei (MN) and nuclear abnormalities (NA) in erythrocytes of peripheral blood. Bioassays taken at 24 or 96 hours in either the cyclophosfamide (CP) or colchicine (COL) showed a significant increase in MN and BC (P values ranging from 0.0499 to 0.0036) compared with information from wild organisms collected over 3 years. Concentrationdependent and time-dependent responses support the proposal of using endemic Xenotoca melanosoma as a bioindicator of genotoxicity and cytotoxicity with a high transcendence for the health of the entire ecosystem and evaluation of the Lerma-Chapala watershed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
GreenFILE |
| Externí odkaz: |
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