An Examination of the Antibiotic Effects of Cylindrospermopsin on Common Gram-Positive and Gram-Negative Bacteria and the Protozoan Naegleria Iovaniensis.

Autor:	Rasmussen, J. Paul¹, Cursaro, Michael², Froscio, Suzanne M.¹, Saint, Christopher P.¹ chris.saint@sawater.com.au
Předmět:	Cyanobacterial toxins Escherichia coli Antibacterial agents Protozoa *Toxicity testing Antibiotics testing Staphylococcus aureus Pseudomonas aeruginosa Naegleria
Zdroj:	Environmental Toxicology. Feb2008, Vol. 23 Issue 1, p36-43. 8p.
Abstrakt:	This article discusses the use of the cyanobacterial toxin, cylindrospermopsin, as a possible antibiotic. According to the authors, the structure of cylindrospermopsin has many elements in common with streptomycin and other antibacterial protein synthesis inhibitors. They tested cylindrospermopsin against Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa by the minimal inhibitory concentration method. They concluded that cylindrospermopsin is not antibacterial at concentrations found in environmental waters, but has some effect on the protozoan Naegleria lovaniensis.
Databáze:	GreenFILE
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