Parameters for Carbamate Pesticide QSAR and PBPK/PD Models for Human Risk Assessment.

Autor: Knaak, James B.1, Dary, Curt C.2, Okino, Miles S.2, Power, Fred W.2, Xiaofei Zhang3, Thompson, Carol B.3, R. Tornero-Velez2, Blancato, Jerry N.2
Předmět:
Zdroj: Reviews of Environmental Contamination & Toxicology. 2008, Vol. 193, p53-210. 158p. 2 Diagrams, 34 Charts, 6 Graphs.
Abstrakt: The article provides parameters for the development of the quantitative structure of physiologically based pharmacokinetic/pharmacodynamic (QSPBPK/PD) models for assessing health risks to carbamates. The quantitative structure-activity relationship model approach required knowledge of the numerical values of the parameters of related chemicals and specification of an equation for conducting the multiple regression analysis.
Databáze: GreenFILE