| Autor: |
Cai, Jiao1,2 (AUTHOR), Yang, Minghan3 (AUTHOR), Zhang, Nan3 (AUTHOR), Chen, Ying1,2 (AUTHOR), Wei, Jianhua4 (AUTHOR), Wang, Jian4 (AUTHOR), Liu, Qixin1 (AUTHOR), Li, Wenjie1 (AUTHOR), Shi, Wenming5 (AUTHOR), Liu, Wei1,2,6,7 (AUTHOR) liuw@cqust.edu.cn |
| Abstrakt: |
Several studies suggested significant associations of residential damp indicators with asthma, rhinitis, and eczema in childhood, but evidences of these associations were not comprehensively reviewed among previous studies in recent years. In this paper, we systematically reviewed and meta-analyzed these studies to summary the state-of-the-art findings on associations of residential damp indicators with asthma, rhinitis, and eczema in childhood. A total of 1579 documents were collected from five database platforms (two English, three Chinese) and 56 original articles were finally retained. Most of these studies were conducted in China during 2010–2023. All meta-analyses among these studies for different damp indicators (visible mold spots, moldy odor, visible damp stains, water damage, window pane condensation, and damp clothing/bedding) suggested significant, consistent, and positive associations of these indicators with the target diseases in childhood. Specifically, the meta-analyses indicate that the increased risks of these damp indicators ranged 19 %–54 % for ever-doctor-diagnosed asthma, 27 %–44 % for ever-reported wheeze, 32 %–57 % for current-reported wheeze, 13 %–34 % for ever-doctor-diagnosed rhinitis, 10 %–15 % for ever-reported rhinitis, 15 %–32 % for current-reported rhinitis, 13 %–51 % for ever-reported eczema, 24 %–38 % for current-reported eczema. Herein, moldy odor generally increased the highest risks of these diseases, following by visible mold spots, water damage, visible damp stains, damp clothing/beddings, and window pane condensation. Our meta-analyses furtherly confirmed that residential dampness-related exposures are risk factors for asthma, wheeze, rhinitis, and eczema in childhood. More attention should be paid on the decreases of residential damp exposures for the prevention of these diseases. [ABSTRACT FROM AUTHOR] |
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