| Autor: |
Abdellatif, Boudra1 afboudra@gmail.com, Rachid, Merati1, Samia, Meliani1, Hebib, Aggad1 |
| Předmět: |
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| Zdroj: |
Fresenius Environmental Bulletin. Oct2023, Vol. 32 Issue 10, p3157-3166. 10p. |
| Abstrakt: |
This study aimed to introduce propolis extract and investigate its potential in promoting osteoconduction and osteoinduction in orthotopic allografts. The experiment was conducted on fifty adult New Zealand breed male rabbits, divided into two groups of fifteen each. The control group received autoclaved allogeneic cortical grafts, while the second group underwent the same procedure with the autoclaved allografts covered by a thin layer of Ethanol Extract of Algerian Propolis (EEPA). The radiological follow-up revealed that the ACWP+12 group was scored higher in callus formation, bone formation, and osteotomy line preservation compared to the control group. In contrast, the control group showed limited osteoinduction and no osteoconduction. The speed of callus passage was also enhanced in the ACWP+12 group compared to commercial propolis and BMP-2 groups. In this work, autoclaving and the shape of the implanted graft were found to affect osteoinductive capacity, but Algerian propolis effectively promoted osteoinduction and osteoconduction. Furthermore the propolis stimulated early cartilage formation and mineralization, shortening the consolidation phase after implantation and improving implant stability. [ABSTRACT FROM AUTHOR] |
| Databáze: |
GreenFILE |
| Externí odkaz: |
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