Invited Perspective: Environmental Chemical-Sensing AHR Remains an Enigmatic Key Player in Toxicology.

Autor:	Kaplan, Barbara L. F.1 bkaplan@cvm.msstate.edu, Lawrence, B. Paige2
Předmět:	*Pollutants *Hydrocarbons *Toxicology Transcription factors
Zdroj:	Environmental Health Perspectives. Mar2023, Vol. 131 Issue 3, p031307-1-031307-2. 2p. 1 Graph.
Abstrakt:	The article considers environmental chemical-sensing aryl hydrocarbon receptor (AHR) as vital regulator in toxicology, citing a study which characterized the immune effects of fine particulate matter (PM) and showed that PM2.5 or indeno[1,2,3-cd]pyrene (IP), as an AHR ligand, modulated immune responses. It points out conflicting result of another study in which AHR ligands suppressed T follicular helper cells in influenza A-infected mice and that different AHR ligands produce different effects.
Databáze:	GreenFILE
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