Aroclor-1260® Effects on In Vitro Fertilization in the Mouse.

Autor:	Wang, X. Q.1, Dukelow, W. R.1
Předmět:	*Polychlorinated biphenyls *Organochlorine compounds *Toxicology *Environmental protection *Applied ecology Fertilization in vitro Ovum Cell communication Cell junctions
Zdroj:	Bulletin of Environmental Contamination & Toxicology. Oct98, Vol. 61 Issue 4, p470-476. 7p. 2 Charts.
Abstrakt:	The article offers information about a study conducted to evaluate the effects of A-1260 on in vitro fertilization of frozen-thawed and fresh oocytes of a mouse. A-1260 is a polychlorinated biphenyls (PCB), which are persistent industrial chemicals of global environmental concern. Intercellular communication between the oocyte and granulosa cells by gap junctions is necessary for oocyte growth in vitro. However, results in the study showed that the PCB have been shown to inhibit gap junctional communications in cultured liver cells and this may be one of the mechanisms causing oocyte degeneration.
Databáze:	GreenFILE
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