Detection of Latex Allergens by Immunoelectron Microscopy in Ambient Air (PM10) in Oslo, Norway (1997-2005).

Autor: Namork, Ellen ellen.namork@fhi.no., Kurup, Viswanath P., Aasvang, Gunn Marit, Johansen, Bjørn V.
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Zdroj: Journal of Environmental Health. Nov2004, Vol. 67 Issue 4, p20-26. 7p. 3 Black and White Photographs, 1 Graph.
Abstrakt: The authors collected ambient air along two highways in Oslo to investigate the annual variations in particulate matter (PM[sub 10]) and the presence of latex as an outdoor allergen. PM[sub 10] was monitored for a period of five years, during which time the use of studded winter tires was reduced. The presence of latex and of common aeroallergens was examined directly on the collection filters with immunoelectron microscopy visualized in a scanning electron microscope. The annual variation in PM[sub 10] was similar over the five years of sampling, with increased mass concentrations in winter. Statistical analysis indicated no major effect from the change to nonstudded tires. The most important factors influencing the PM[sub 10] concentration were meteorological parameters like wind and rain. Immunolabeling of the filters showed latex as an outdoor allergen that adhered to carbon aggregates from vehicle emission. The results also indicated cross-reactive epitopes among the common allergens investigated, which for sensitized subjects may add to the risk of developing latex allergy. [ABSTRACT FROM AUTHOR]
Databáze: GreenFILE
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