| Autor: |
Bosker, Thijs1, Munkittrick, Kelly R.1, Lister, Andrea2, MacLatchy, Deborah L.2 |
| Předmět: |
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| Zdroj: |
Environmental Toxicology & Chemistry. May2016, Vol. 35 Issue 5, p1107-1112. 6p. |
| Abstrakt: |
17α-Ethinylestradiol (EE2) is a potent estrogen used in birth-control pills. Previous laboratory and field studies have shown negative impacts in a variety of fish species after exposure to low levels of EE2, most notably a nearly complete shutdown of egg production. The present study demonstrates that mummichog ( Fundulus heteroclitus), a small-bodied estuarine species, is able to continue to produce eggs after exposure for 28 d to 100 ng of EE2/L. No effect of EE2 on egg production was observed, whereas a >35-fold increase in vitellogenin ( vtg 1) gene expression in males was found. The lack of response in egg production in fish exposed to high levels of EE2 warrants further investigations on species-specific responses to estrogens and endocrine disruptors in general. Environ Toxicol Chem 2016;35:1107-1112. © 2015 SETAC [ABSTRACT FROM AUTHOR] |
| Databáze: |
GreenFILE |
| Externí odkaz: |
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