Autor: |
Cronin, Mark T.D.1, Jaworska, Joanna S.2, Walker, John D.3, Comber, Michael H.I.4, Watts, Christopher D.5, Worth, Andrew P.6 |
Předmět: |
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Zdroj: |
Environmental Health Perspectives. Aug2003, Vol. 111 Issue 10, p1391-1401. 11p. |
Abstrakt: |
This article is a review of the use of quantitative (and qualitative) structure-activity relationships (QSARs and SARs) by regulatory agencies and authorities to predict acute toxicity, mutagenicity, carcinogenicity, and other health effects. A number of SAR and QSAR applications, by regulatory agencies and authorities, are reviewed. These include the use of simple QSAR analyses, as well as the use of multivariate QSARs, and a number of different expert system approaches. [ABSTRACT FROM AUTHOR] |
Databáze: |
GreenFILE |
Externí odkaz: |
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