Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jean E. Rivier"'
Autor:
Betty R. McConn, Kouassi R. Kpodo, Jean E. Rivier, Dominic P. Behan, Brian T. Richert, John S. Radcliffe, Donald C. Lay, Jay S. Johnson
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The study objective was to evaluate the interaction between corticotrophin releasing factor (CRF) receptor signaling and prophylactic antibiotic administration on intestinal physiology in newly weaned and transported pigs. Pigs (n = 56; 5.70 ± 1.05
Externí odkaz:
https://doaj.org/article/612fa2e004574c2bb7ec2d63bf038080
Autor:
Roberto Jappelli, Marilyn H Perrin, Kathy A Lewis, Joan M Vaughan, Christos Tzitzilonis, Jean E Rivier, Wylie W Vale, Roland Riek
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84013 (2014)
Corticotropin-Releasing Factor Receptors (CRFRs) are class B1 G-protein-coupled receptors, which bind peptides of the corticotropin releasing factor family and are key mediators in the stress response. In order to dissect the receptors' binding speci
Externí odkaz:
https://doaj.org/article/b0a3342705b14838a2d1dd64b266fc0e
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e63942 (2013)
The role of brain corticotropin-releasing factor type 2 (CRF2) receptors in behavioral stress responses remains controversial. Conflicting findings suggest pro-stress, anti-stress or no effects of impeding CRF2 signaling. Previous studies have used a
Externí odkaz:
https://doaj.org/article/cca0bac2122b4ee8af9da47e19713678
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39935 (2012)
Psychological stress is a predisposing factor in the onset and exacerbation of important gastrointestinal diseases including irritable bowel syndrome (IBS) and the inflammatory bowel diseases (IBD). The pathophysiology of stress-induced intestinal di
Externí odkaz:
https://doaj.org/article/f595e22590a045e4aa0dcf261c5b3210
Publikováno v:
PLoS Biology, Vol 6, Iss 2, p e17 (2008)
Amyloids are highly organized protein aggregates that are associated with both neurodegenerative diseases such as Alzheimer disease and benign functions like skin pigmentation. Amyloids self-polymerize in a nucleation-dependent manner by recruiting t
Externí odkaz:
https://doaj.org/article/7918550dc63b47fdac5f182210f641a5
Publikováno v:
The Journal of comparative neurology. 525(18)
The corticotropin-releasing factor (CRF) family of peptides includes CRF and three urocortins, which signal through two distinct G-protein coupled receptors, CRF
Autor:
Jean E. Rivier, Bruce A. Adams, A. Grey Craig, Carol M. Warby, Minkyu Park, Nancy M. Sherwood, Wolfgang Fischer, Elaine D. Vickers
Publikováno v:
Biology of Reproduction. 67:232-239
Multiple forms of GnRH within individual brains may have different functions. However, some vertebrates such as salmonids continue to reproduce even though they have lost or do not express 1 of the 3 forms of GnRH found in most other teleosts. We exa
Autor:
Karel Konvicka, Tony Yuen, Robert P. Millar, Stuart C. Sealfon, Colleen A. Flanagan, Ling Chi, Harel Weinstein,#,◆ and, Vladimir Rodic, Jean E. Rivier
Publikováno v:
Biochemistry. 39:8133-8141
Mutation of Asp(2.61(98)) at the extracellular boundary of transmembrane helix 2 of the gonadotropin-releasing hormone (GnRH) receptor decreased the affinity for GnRH. Using site-directed mutagenesis, ligand modification, and computational modeling,
Publikováno v:
Protein & Peptide Letters. 3:219-224
Abstract: Title glycine derivatives FmocNRlCH(NR2Boc)CO2H (I; Fmoc =9-fluorenyl-methyloxycarbonyl; Boc = Me3CO2C; Rl = H, Me; R2 = H, Me), useful as templates for the introduction of desired functionalities into peptides, were prepared by condensatio
Publikováno v:
Fertility and Sterility. 64:139-145
Objective To test the hypothesis that over a 4-week treatment period, Nal-Glu GnRH antagonist ([AcD2Nal 1 , D4ClPhe 2 , D3Pal 3 , Arg 5 , DGlu 6 [AA], DAla 10 ] GnRH) at a dose of 200 μ g/kg per day SC would suppress levels of immunologically active