Evaluation of rapidarc (volumetric modulated arc therapy) and the impact of set-up error in the treatment of head and neck cancer

Autor: Teoh, E. E. May
Rok vydání: 2014
Předmět:
Druh dokumentu: Electronic Thesis or Dissertation
Popis: RapidArc (Volumetric Modulated Arc Therapy) is an advanced radiotherapy technique which can achieve excellent target volume coverage and organ at risk (OAR) sparing. The potential role of RapidArc in the treatment of head and neck cancer (HNC) was evaluated by planning studies comparing RapidArc with fixed gantry IMRT, and a prospective study to assess clinical outcomes in patients treated with RapidArc. In the planning study evaluating oropharyngeal tumours, RapidArc achieved comparable dose distributions to IMRT with significantly improved dose conformity and reduced monitor units {M Us). However, in the study evaluating nasopharyngeal and paranasal sinus tumours, target volume coverage and sparing of some OARs were marginally inferior with RapidArc. Preliminary results have indicated that toxicity is acceptable in patients treated" with RapidArc and comparable to fixed gantry IMRT.
Databáze: Networked Digital Library of Theses & Dissertations