The application of 3-d dosimetry in brachytherapy treatment

Autor: Wai, Philip
Rok vydání: 2007
Předmět:
Druh dokumentu: Electronic Thesis or Dissertation
Popis: In the UK, prostate cancer is the second most commonly occurring cancer in men.. The number of prostate cancer incidents is expected to increase due to improved screening and diagnostic techniques, whilst the mortality rate continues to fall as the variety ofavailable treatments increases. This research focuses on the commonly used brachytherapy seed OncoSeed™ Model 6711 manufactured by GE Healthcare. lodine-125 seeds are surgically implanted and left inside the prostate permanently to obtain local control of the malignant prostate cancer. Prior to the surgical procedure, a treatment plan is created on a computer planning system. There is currently no 3-D method to verify whether the planning system model matches the actual delivery ofradiation dose to the prostate. This study is presented as a typical case study of what can be achieved using solid polymer dosimetry. Experimental results are presented comparing solid polymer dosimetry using Optical-CT with radiochromic films (RCF) and Monte Carlo simulations. Initial Optical-CT results have shown good agreement to Monte Carlo, radiochromic films and comparable to previously published data.
Databáze: Networked Digital Library of Theses & Dissertations