Intermolecular interactions of general anaesthetics with cell membranes; effects on microdomains and the membrane dipole potential

Autor: Jamal, Ghadir A.
Rok vydání: 2008
Předmět:
Druh dokumentu: Electronic Thesis or Dissertation
Popis: General anaesthetic agents (GAs) have been used clinically for over a century, yet their mechanisms of actions remain a matter of debate. GAs affect a wide range of membrane lipid components but the actual molecular nature underlying the functional effect is yet to be explained. GAs are believed to alter the flow of sodium ions into neurons through the cell membrane. However, exactly how the anaesthetics achieve this is not yet fully understood.
Databáze: Networked Digital Library of Theses & Dissertations