Low-biofouling ultrafiltration membrane fabricated by blending polysulfone with amphapathic and zwitterionic copolymer MAO-DMAPA
| Autor: | To-yu Wang, 王拓愚 |
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| Rok vydání: | 2013 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 101 In recent years, the zwitterionic copolymers were paid much attention to use for modifying the membranes for the purpose of antifouling. In our study, we have designed an amphiphilic and zwitterionic copolymer MAO-DMAPA synthesized from poly(maleic anhydride-alt-1-octadecene) (MAO) and 3-(dimethylamino)-1-propylamine (DMAPA), then we used different MAO-DMAPA content to blend with polysulfone (PSf) and fabricate the ultrafiltration (UF) membrane by the non-solvent induced phase separation (NIPS) method under 0% and 70% EtOH/H2O mixture surrounding. After membrane preparation, we use the bovine serum albumin(BSA) and lysozyme to measure the protein adsorption resistance of membranes. For these two proteins, we found that the maximum of protein binding capacity and dissociation constant were decreased with elevating the blended MAO-DMAPA content. Finally, we found that the membrane formed under 70% EtOH has superior protein resistance. Then we did the MAO-DMPA titration curve to distinguish the pKa value of the tertiary amine and carboxyl group on MAO-DMAPA. According to the titration curve, we conducted the protein resistance of blended MAO-DMAPA membranes at different pH value surroundings by protein filtration. We got that 70% M-3.6 has higher flux and the best low-protein adsorption ability of those membranes. After protein adsorption experiment, we choose the 70% M-3.6 to carry out E.coli. adhesion. From the result, we can find that 70% M-3.6 has lower amount of E.coli. colonies than M-0. Therefore, we verify blending MAO-DMAPA contributed to improve the low-biofouling ability. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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