Metabolic syndrome and evaluation of energy expenditure in patients with systemic lupus erythematosu
| Autor: | Lin, Ging-Yi, 林靖怡 |
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| Rok vydání: | 2009 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 97 Systemic lupus erythematosus (SLE) is a chronic disease of the immune system. The main characteristic of SLE is that the autoimmune system becomes abnormal, SLE causes damage to skin, cardiovascular system, lungs, kidney, skeletons and gastrointestinal etc. The complication of SLE will spread through all organs. The main concern of SLE patients is increasing the risk of cardiovascular diseases and osteoporosis. The index of metabolic syndrome (MS) is a direct or indirect risk factor of cardiovascular diseases including heart failure, coronary heart disease, arteriosclerosis and stroke. The aim of this study was to find the relationship between the physical activity levels of SLE patients and metabolic syndrome. The subjects of the study were 43 female SLE patients. They worn RT3 triaxial accelerometer to record their physical activity for 7 days in order to elucidate the relationship among the index of MS (Waist, blood pressure, blood glucose, serum high density lipoprotein, triglyceride), total calories, activity calories, total calories/Kg, and activity Calories/Kg. We found that BMI, total calories, activity calories in SLE patients with MS was significantly higher than SLE patients without MS(P＜0.001). But total calories/Kg in SLE patients with MS is lower than SLE patients without MS(P＜0.05). Blood glucose, total serum cholesterol and triglyceride did not have significant difference. BMI of the high activity calories group are more than the low activity calories group (22.34 ± 3.97 VS. 26.36 ± 4.27 Kg/m2, P＜0.05). BMI of the low total calories/Kg group are more than the high total calories/Kg group (25.48 ± 4.54 VS. 20.92 ± 2.58 Kg/m2, P＜0.05). HDL-C of the high activity calories/Kg group was more than the low activity calories/Kg group (75.14 ± 21.30 VS. 61.52 ± 16.48 mg/dl, P＜0.05). TC/HDL-C of the high activity calories/Kg group was less than the low activity calories/Kg group (2.78 ± 0.47 VS. 3.27 ± 0.80, P＜0.05). The results were significant differences (P＜0.05). In conclusions, we found that increasing physical activity is benefit for SLE patients in this study. Increasing physical activity can improve serum high density lipoprotein level, triglyceride and TC/HDL-C for SLE patients. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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