Mechanisms of the proliferate effects of Huangqi onRsc 96 peripheral Schwann cells

Autor: Fu-Yang Ko, 柯富揚
Rok vydání: 2008
Druh dokumentu: 學位論文 ; thesis
Popis: 96
The aim of the present study was to evaluate the proliferative effects of huangqi on neuron regeneration. RSC96, Schwann cells. We investigate the molecular mechanisms, which include :(1) proliferative signaling, HGF-cMET-Cell cycle factors and EGFR-MEK-ERK pathways, and survival signaling. (2) anti-scar signaling, FGF-2-UPA-MMPs. After treat with different concentrations (1.25μg/ml,12.5μg/ml,125μg/ml,250μg/ml,500μg/ml) of Huangqi, we confirmed it can increase Rsc 96 cell proliferation in the best concentration of 12.5μg/ml(P
Databáze: Networked Digital Library of Theses & Dissertations