Mechanisms of the proliferate effects of Huangqi onRsc 96 peripheral Schwann cells
Autor: | Fu-Yang Ko, 柯富揚 |
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Rok vydání: | 2008 |
Druh dokumentu: | 學位論文 ; thesis |
Popis: | 96 The aim of the present study was to evaluate the proliferative effects of huangqi on neuron regeneration. RSC96, Schwann cells. We investigate the molecular mechanisms, which include :(1) proliferative signaling, HGF-cMET-Cell cycle factors and EGFR-MEK-ERK pathways, and survival signaling. (2) anti-scar signaling, FGF-2-UPA-MMPs. After treat with different concentrations (1.25μg/ml,12.5μg/ml,125μg/ml,250μg/ml,500μg/ml) of Huangqi, we confirmed it can increase Rsc 96 cell proliferation in the best concentration of 12.5μg/ml(P |
Databáze: | Networked Digital Library of Theses & Dissertations |
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