Sex Differences in Initiation and Expression of Methylplhenidate Sensitization in Adolescent Rats: Analysis of Accumbal and Striatal BDNF
Autor: | Roeding, Ross L., Perna, Marla K., Brown, Russell W. |
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Předmět: | |
Zdroj: | ETSU Faculty Works. |
Druh dokumentu: | Text |
Popis: | This study analyzed locomotor sensitization to methylphenidate (MPH, Trade name: Ritalin) in adolescent male and female rats. Females, but not males, demonstrated locomotor sensitization. Interestingly, females given MPH demonstrated a significant decrease of brain derived neurotrophic factor (BDNF) in the striatum, whereas males demonstrated an increase in this same brain area. |
Databáze: | Networked Digital Library of Theses & Dissertations |
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