Development of a Diagnostic Clinical Score for Hemodynamically Significant Patent Ductus Arteriosus
Autor: | Kindler, Annemarie, Seipolt, Barbara, Heilmann, Antje, Range, Ursula, Rüdiger, Mario, Hofmann, Sigrun Ruth |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
arterieller Gang
klinischer Diagnosewert Echokardiographie Ductus arteriosus Botalli Frühgeborene sehr niedriges Geburtsgewicht TU Dresden Publikationsfond arterial duct clinical diagnostic score echocardiography ductus arteriosus Botalli premature infants very low birth weight Publishing Fund ddc:610 rvk:XA 10000 |
Zdroj: | Frontiers in Pediatrics (2017), 5, ISSN: 2296-2360. DOI: 10.3389/fped.2017.00280. Artikelnr.: 280. |
Druh dokumentu: | Článek |
Popis: | There is no consensus about the hemodynamic significance and, therefore, the need to treat a persistent ductus arteriosus in preterm newborns. Since the diagnosis of a hemodynamically significant persistent ductus arteriosus (hsPDA) is made by a summary of non-uniform echo-criteria in combination with the clinical deterioration of the preterm neonate, standardized clinical and ultrasound scoring systems are needed. The objective of this study was the development of a clinical score for the detection and follow-up of hsPDA. In this observational cohort study of 154 preterm neonates (mean gestational age 28.1 weeks), clinical signs for the development of hsPDA were recorded in a standardized score and compared to echocardiography. Analyzing the significance of single score parameters compared to the diagnosis by echocardiography, we developed a short clinical score (calculated sensitivity 84% and specificity 80%). In conclusion, this clinical diagnostic PDA score is non-invasive and quickly to implement. The continuous assessment of defined clinical parameters allows for a more precise diagnosis of hemodynamic significance of PDA and, therefore, should help to detect preterm neonates needing PDA-treatment. The score, therefore, allows a more targeted use of echocardiography in these very fragile preterm neonates. |
Databáze: | Networked Digital Library of Theses & Dissertations |
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