The impact of tunnel mutations on enzymatic catalysis depends on the tunnel-substrate complementarity and the rate-limiting step

Autor: Kokkonen, Piia, Slanska, Michaela, Dockalova, Veronika, Pinto, Gaspar P., Sánchez-Carnerero, Esther M., Damborsky, Jiri, Klán, Petr, Prokop, Zbynek, Bednar, David
Zdroj: In Computational and Structural Biotechnology Journal 2020 18:805-813
Databáze: ScienceDirect