DNA topology regulates PAM-Cas9 interaction and DNA unwinding to enable near-PAMless cleavage by thermophilic Cas9

Autor: Shi, Ya-Jing, Duan, Min, Ding, Jun-Mei, Wang, Fan-Qi, Bi, Li-Li, Zhang, Cai-Xiang, Zhang, Yi-Zhou, Duan, Jun-Yi, Huang, An-Hui, Lei, Xin-Lin, Yin, Hao, Zhang, Ying
Zdroj: In Molecular Cell 3 November 2022 82(21):4160-4175
Databáze: ScienceDirect