Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1β and oncostatin M pre-treated non-sclerotic osteoblasts
| Autor: | Sanchez, C. †, Deberg, M.A. †, Piccardi, N. ‡, Msika, P. ‡, Reginster, J.-Y.L. †, Henrotin, Y.E. † |
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| Zdroj: | In Osteoarthritis and Cartilage November 2005 13(11):979-987 |
| Databáze: | ScienceDirect |
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