Discovery of orally efficacious RORγt inverse agonists. Part 2: Design, synthesis, and biological evaluation of novel tetrahydroisoquinoline derivatives

Autor: Kono, Mitsunori, Oda, Tsuneo, Tawada, Michiko, Imada, Takashi, Banno, Yoshihiro, Taya, Naohiro, Kawamoto, Tetsuji, Tokuhara, Hidekazu, Tomata, Yoshihide, Ishii, Naoki, Ochida, Atsuko, Fukase, Yoshiyuki, Yukawa, Tomoya, Fukumoto, Shoji, Watanabe, Hiroyuki, Uga, Keiko, Shibata, Akira, Nakagawa, Hideyuki, Shirasaki, Mikio, Fujitani, Yasushi, Yamasaki, Masashi, Shirai, Junya, Yamamoto, Satoshi
Zdroj: In Bioorganic & Medicinal Chemistry 15 January 2018 26(2):470-482
Databáze: ScienceDirect