Phosphonate-based irreversible inhibitors of human γ-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity

Autor: Kamiyama, Akane, Nakajima, Mado, Han, Liyou, Wada, Kei, Mizutani, Masaharu, Tabuchi, Yukiko, Kojima-Yuasa, Akiko, Matsui-Yuasa, Isao, Suzuki, Hideyuki, Fukuyama, Keiichi, Watanabe, Bunta, Hiratake, Jun
Zdroj: In Bioorganic & Medicinal Chemistry 1 November 2016 24(21):5340-5352
Databáze: ScienceDirect
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