A phenotypic drug discovery study on thienodiazepine derivatives as inhibitors of T cell proliferation induced by CD28 co-stimulation leads to the discovery of a first bromodomain inhibitor

Autor: Endo, Junichi, Hikawa, Hidemasa, Hamada, Maiko, Ishibuchi, Seigo, Fujie, Naoto, Sugiyama, Naoki, Tanaka, Minoru, Kobayashi, Haruhito, Sugahara, Kunio, Oshita, Koichi, Iwata, Kazunori, Ooike, Shinsuke, Murata, Meguru, Sumichika, Hiroshi, Chiba, Kenji, Adachi, Kunitomo
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 March 2016 26(5):1365-1370
Databáze: ScienceDirect