Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors

Autor:	Arcari, Joel T., Beebe, Jean S., Berliner, Martin A., Bernardo, Vincent, Boehm, Merin, Borzillo, Gary V., Clark, Tracey, Cohen, Bruce D., Connell, Richard D., Frost, Heather N., Gordon, Deborah A., Hungerford, William M., Kakar, Shefali M., Kanter, Aaron, Keene, Nandell F., Knauth, Elizabeth A., LaGreca, Susan D., Lu, Yong, Martinez-Alsina, Louis, Marx, Matthew A., Morris, Joel, Patel, Nandini C., Savage, Doug, Soderstrom, Cathy I., Thompson, Carl, Tkalcevic, George, Tom, Norma J., Vajdos, Felix F., Valentine, James J., Vincent, Patrick W., Wessel, Matthew D., Chen, Jinshan M.
Zdroj:	In Bioorganic & Medicinal Chemistry Letters 15 May 2013 23(10):3059-3063
Databáze:	ScienceDirect
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect