Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1)

Autor:	Wu, Shung C. a, ⁎, Yoon, David a, Chin, Janice c, van Kirk, Katy b, Seethala, Ramakrishna a, Golla, Rajasree a, He, Bin a, Harrity, Thomas a, Kunselman, Lori K. a, Morgan, Nathan N. a, Ponticiello, Randolph P. a, Taylor, Joseph R. a, Zebo, Rachel a, Harper, Timothy W. a, Li, Wenying b, Wang, Mengmeng a, Zhang, Lisa a, Sleczka, Bogdan G. b, Nayeem, Akbar a, Sheriff, Steven b, Camac, Daniel M. b, Morin, Paul E. b, Everlof, John G. b, Li, Yi-Xin a, Ferraro, Cheryl A. c, Kieltyka, Kasia c, Shou, Wilson c, Vath, Marianne B. c, Zvyaga, Tatyana A. c, Gordon, David A. a, Robl, Jeffrey A. a
Zdroj:	In Bioorganic & Medicinal Chemistry Letters 2011 21(22):6693-6698
Databáze:	ScienceDirect
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect