Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor

Autor: Liang, Xiaofei, Li, Feng, Chen, Cheng, Jiang, Zongru, Wang, Aoli, Liu, Xiaochuan, Ge, Juan, Hu, Zhenquan, Yu, Kailin, Wang, Wenliang, Zou, Fengming, Liu, Qingwang, Wang, Beilei, Wang, Li, Zhang, Shanchun, Wang, Yuxin, Liu, Qingsong, Liu, Jing
Zdroj: In European Journal of Medicinal Chemistry 5 August 2018 156:831-846
Databáze: ScienceDirect