Clonal variation in productivity and proteolytic clipping of an Fc-fusion protein in CHO cells: Proteomic analysis suggests a role for defective protein folding and the UPR

Autor: Henry, Michael, Gallagher, Clair, Kelly, Ronan M., Frye, Christopher C., Osborne, Matthew D., Brady, Ciaran P., Barron, Niall, Clynes, Martin, Meleady, Paula
Zdroj: In Journal of Biotechnology 10 September 2018 281:21-30
Databáze: ScienceDirect