In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-κB and activation of caspase-8.
| Autor: | Gentle, Ian E., Wong, W. Wei-Lynn, Evans, Joseph M., Bankovacki, Alexandra, Cook, Wendy D., Khan, Nufail R., Nachbur, Ulrich, Rickard, James, Anderton, Holly, Moulin, Maryline, Lluis, Josep Maria, Moujalled, Donia M., Silke, John, Vaux, David L. |
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| Zdroj: | In Journal of Biological Chemistry 29 January 2016 291(5):2547-2547 |
| Databáze: | ScienceDirect |
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