Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations

Autor: Segditsas, Stefania, Sieber, Oliver M., Rowan, Andrew, Setien, Fernando, Neale, Kay, Phillips, Robin K.S., Ward, Robyn, Esteller, Manel, Tomlinson, Ian P.M.
Zdroj: In Experimental and Molecular Pathology 2008 85(3):201-206
Databáze: ScienceDirect