Intrathecally injected Ile-Pro-Ile, an inhibitor of membrane ectoenzyme dipeptidyl peptidase IV, is antihyperalgesic in rats by switching the enzyme from hydrolase to synthase functional mode to generate endomorphin 2

Autor: Király, Kornél, Szalay, Balázs, Szalai, Judit, Barna, István, Gyires, Klára, Verbeken, Mathieu, Rónai, András Z.
Zdroj: In European Journal of Pharmacology 2009 620(1):21-26
Databáze: ScienceDirect